Craig C.Mello

2006 Nobel Laureate in Physiology or Medicine

Craig C. Mello, American Biologist, professor in the Program in Molecular Medicine at the University of Massachusetts Medical School. He was awarded the 2006 Nobel Prize for Physiology or Medicine, along with Andrew Z. Fire, for their discovery of RNA interference - gene silencing by double-stranded RNA.


Mello, Fire and their colleagues reported that double-stranded RNA could induce sequence-specific gene silencing. RNAi occurs in plants, animals and humans. RNAi can spread between cells and can even be inherited. It is of great importance for the regulation of gene expression, and it may lead to many novel therapies in the future.

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